Sequence and lineage
The Thr-Lys-Pro-Arg-Pro-Gly-Pro sequence embeds the tuftsin motif with a Pro-Gly-Pro tail — the defining structural modification of the analog.
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Compound profile
Ancillary & lab suppliesSelank
Synthetic Thr-Lys-Pro-Arg-Pro-Gly-Pro heptapeptide — a tuftsin-analog reference peptide for structural and enzymatic-stability studies in vitro.
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic analog of the tetrapeptide tuftsin, extended with a Pro-Gly-Pro C-terminal tail that improves metabolic stability. It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, and most of its literature comes from the Russian analytical tradition — sequence work, stability studies and receptor-interaction assays in vitro.
Structure and class
Structurally, Selank is tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension; the extension measurably changes the peptide's proteolytic-resistance profile in enzyme assays. Laboratory work with the compound centers on this structure–stability relationship and on documented in-vitro assay conditions.
Chemistry and analytical notes
Notes cover structural and analytical chemistry; each link runs a live PubMed search for the topic.
Proteolytic stability
Enzyme assays compare Selank's degradation kinetics with those of the parent tetrapeptide, quantifying the contribution of the C-terminal extension.
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MS confirms the heptapeptide mass and HPLC the purity of each batch, with results recorded on the batch certificate of analysis.
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Selank is frequently analyzed alongside Semax in comparative structural studies of Pro-Gly-Pro-extended peptide analogs.
Search PubMedHandling & storage
Store lyophilized at −20°C, protected from light and moisture. Reconstitute with reconstitution-grade sterile water under aseptic technique; keep the solution at 2–8°C, avoid repeated freeze–thaw cycles and use within your protocol's stability window. For laboratory research use only — not for human or veterinary use.
For laboratory research use only
All products are sold strictly for laboratory research purposes only. Not for human or veterinary consumption, diagnostic, or therapeutic use. The information on this page is a chemistry and handling summary for qualified researchers — it is not medical advice, and nothing here constitutes a claim of safety or efficacy in humans.
Selank
Source this compound for your laboratory
Every batch is released only at ≥99% HPLC purity with an MS identity check, registered against a batch number you can verify online before you open the vial.